Ajinomoto Aminoscience LLC introduces AminoStable™, L-Alanyl-L-Glutamine, Dipeptide

RALEIGH, NC.,March 28/KYODO JBN/—AminoStable™, L-Alanyl-L-Glutamine, is available for medical use, human consumption and for use in cell culture media

Ajinomoto Aminoscience LLC, the global leader in the amino acid marketplace today announced the introduction of AminoStable™, for use in pharmaceutical applications and for the cell culture market. AminoStable™ is L-Alanyl-L-Glutamine manufactured via a novel and efficient enzymatic method. This newly discovered method is a simple, cost effective process that produces peptides in high yield.

Research has shown that Glutamine has many potential healthcare benefits; however use has been limited due to its lack of stability, especially in solution. The dipeptide, AminoStable™, stabilizes the L-Glutamine in solution. Other forms of L-Alanyl-L-Glutamine are available, however high costs have severely limited usage. Ajinomoto's new, efficient production processes addresses this issue. Ajinomoto expects the introduction of AminoStable™ will lead to increased use of L-Alanyl-L-Glutamine in pharmaceutical products, especially intravenous solutions and other application where increased use of L-Glutamine could result in improved patient care. The introduction of AminoStable™ is also expected lead to increased usage of L-Alanyl-L-Glutamine in cell culture media.

AminoStable™ will file for Drug Master File approval from the U.S. Food and Drug Administration (FDA). Once approved, pharmaceutical and biotech companies will be able to use AminoStable as an Active Pharmaceutical Ingredient in their medications and other medical specialty products.

Ajinomoto will produce AminoStable™ in its facility located in Raleigh, NC. This is the only US facility that produces pharmaceutical grade amino acids under cGMP conditions. Sales of AminoStable™ will begin in late March.

ABOUT AJINOMOTO AMINOSCIENCE LLC
Ajinomoto AminoScience LLC (www.ajiaminoscience.com) is a part of Ajinomoto USA, Inc., a wholly owned subsidiary of Ajinomoto Co., Inc. The Raleigh, NC plant has been in operation since 1982 and continues to be the only pharmaceutical L-amino acid manufacturer in the United States. In addition, the facility offers patented amino acid production technology, full capacity operations 7/24/365, secured supply lines and warehouse facilities, blending and pulverization services, complete analytical and technical support, non-animal manufacturing, operation under current Good Manufacturing Practices (cGMP), and custom labeling and packaging. Being a subsidiary of Ajinomoto Co., Inc, allows for global sourcing and pricing. Our parent company continues to lead the industry in production technology, global supply and nutrition research for amino acids.